T2K reports its first results in the search for CP violation in neutrino oscillations using appearance and disappearance channels for neutrino- and antineutrino-mode beam. The data include all runs from Jan 2010 to May 2016 and comprise 7.482×10207.482×1020,protons on target in neutrino mode, which yielded in the far detector 32 e-like and 135 μμ-like events, and 7.471×10207.471×1020,protons on target in antineutrino mode which yielded 4 e-like and 66 μμ-like events. Reactor measurements of sin22θ13sin22θ13 have been used as an additional constraint. The one-dimensional confidence interval at 90% for δCPδCP spans the range (−3.13−3.13, −0.39−0.39) for normal mass ordering. The CP conservation hypothesis (δCP=0,πδCP=0,π) is excluded at 90% C.L.